Synthetic Route of 52409-22-0, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.52409-22-0, Name is Pd2(DBA)3, molecular formula is C51H42O3Pd2. In a Article£¬once mentioned of 52409-22-0
Reactivity of Planar-Chiral alpha-Ferrocenyl Carbocations towards Electron-Rich Aromatics
The reaction of the enantiopure, planar-chiral alpha-ferrocenyl carbocation (Sp)-2-(P(=S)Ph2)FcCH2+ (Fc = Fe(eta5-C5H5)(eta5-C5H3)) towards electron-rich arenes C6H5E (E = NH2, NMe2, NiPr2, NPh2, PPh2, P(=S)Ph2, OH, SH, SMe) regarding either a nucleophilic attack of the group E or an electrophilic aromatic substitution reaction of the arene at the CH2+ unit is reported. It was found that the amino, oxo or thio functionalities gave the respective ferrocenes in various product distributions, while the P-based species didn’t. Appropriate thiophosphine derivatives could be reduced to their PIII species that were applied as supporting ligands in atropselective C,C cross-coupling reactions for the synthesis of sterically hindered biaryls, where sandwich compound (Sp)-1-(PPh2)-2-(o-NMe2-C6H4)CH2-Fc gave an ee of 69 % (1 mol-% [Pd]), which is up to date the highest observed value for planar-chiral ferrocenes. The absolute configuration of the chiral ferrocenes was confirmed by single-crystal X-ray diffraction analysis. For seleno phosphane 1-(P(=Se)Ph2)-2-(CH2OH)-Fc a unique Se single-atom transfer occurred within its reaction with Sanger’s reagent. The presence of two chemically different Se atoms in 1-(P(=Se)Ph2)-2-(((2,4-(NO2)2-C6H3)Se)CH2)-Fc was confirmed by 77Se{1H} NMR spectroscopy and single-crystal X-ray diffraction analysis, respectively.
A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 52409-22-0
Reference£º
Chapter 1 An introduction to palladium catalysis,
Palladium/carbon catalyst regeneration and mechanical application method