Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments. Computed Properties of C34H28O2Pd. Introducing a new discovery about 32005-36-0, Name is Bis(dibenzylideneacetone)palladium
On the formation of Pd(II) complexes of Trost modular ligand involving N-H activation or P,O coordination in Pd-catalyzed allylic alkylations
Specific chiral ligands have been designed by Trost et al. to perform enantioselective Pd-catalyzed allylic alkylations. It is shown that the Pd(0) complex formed by addition of the Trost ligand (4) to Pd0(dba)2 is not stable in most solvents (acetone, DMF, CH2Cl2). Indeed, Pd0(dba)(4) leads to the formation of a stable PdII complex 5 (X-ray structure), likely by activation of the two N-H bonds of the ligand by the Pd0 centre. The formation of the PdII complex competes with the reaction of Pd0(4) with (E)-PhCH{double bond, long}CH-CH(OAc)-Ph, excluding any investigation of the kinetics of the latter reaction. The ionization steps from intermediate (eta2-PhCH{double bond, long}CH-CH(OAc)-Ph)Pd0(4) were found to be very slow. The cationic P,P complex [(eta3-Ph-CH-CH-CH-Ph)Pd(4)]+, expected to be generated by addition of 2 equiv. of 4 to the precursor [(eta3-Ph-CH-CH-CH-Ph)Pd(mu-Cl)]2, in the presence of a chloride scavenger, leads to a complex mixture whereas addition of 1 equiv. of 4 affords a stable bis-cationic PdII complex {[(eta3-Ph-CH-CH-CH-Ph)Pd]2(4)]}2+, 2 (BF4-) (X-ray structure) via a P,O complexation of each allyl-Pd moieties. This dissymmetric P,O coordination will favour the enantioselectivity of Pd-catalyzed allylic alkylation of (E)-PhCH{double bond, long}CH-CH(OAc)-Ph by the control of the regioselectivity of the nucleophilic attack onto the allylic ligand which is responsible of the enantioselectivity of the overall catalytic reaction.
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.Computed Properties of C34H28O2Pd, you can also check out more blogs about32005-36-0
Reference£º
Chapter 1 An introduction to palladium catalysis,
Palladium/carbon catalyst regeneration and mechanical application method