Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments. Formula: C32H56Cl2N2P2Pd. Introducing a new discovery about 887919-35-9, Name is Bis(di-tert-butyl(4-dimethylaminophenyl)phosphine)dichloropalladium(II)
A novel methodology for the synthesis of highly substituted pyridines based on the palladium-catalyzed enolate alpha-alkenylation of ketones is presented; the formation of aromatic compounds is a new direction for this catalytic C-C bond forming reaction. In the key step, a protected beta-haloalkenylaldehyde participates in alpha-alkenylation with a ketone to afford a 1,5-dicarbonyl surrogate, which then undergoes cyclization/double elimination to the corresponding pyridine product, all in one pot. The beta-haloalkenylaldehyde starting materials can be obtained from the corresponding methylene ketone via Vilsmeier haloformylation. Using this concise route, a variety of highly substituted pyridines were synthesized in three steps from commercially available compounds. (Chemical Equation Presented).
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.Formula: C32H56Cl2N2P2Pd, you can also check out more blogs about887919-35-9
Reference：
Chapter 1 An introduction to palladium catalysis,
Palladium/carbon catalyst regeneration and mechanical application method