Recio, Antonio; Tunge, Jon A. published an article about the compound: 2-Cyano-2-methylpropanoic acid( cas:22426-30-8,SMILESS:CC(C)(C#N)C(O)=O ).SDS of cas: 22426-30-8. Aromatic heterocyclic compounds can be classified according to the number of heteroatoms or the size of the ring. The authors also want to convey more information about this compound (cas:22426-30-8) through the article.
Palladium-catalyzed decarboxylative α-allylation of nitriles readily occurs with use of Pd2(dba)3 and rac-BINAP. This catalyst mixture also allows the highly regiospecific α-allylation of nitriles in the presence of much more acidic α-protons. Thus, the reported method provides access to compounds that are not readily available via base-mediated allylation chemistries. Lastly, mechanistic investigations indicate that there is a competition between C- and N-allylation of an intermediate nitrile-stabilized anion and that N-allylation is followed by a rapid [3,3]-sigmatropic rearrangement.
If you want to learn more about this compound(2-Cyano-2-methylpropanoic acid)SDS of cas: 22426-30-8, you may wish to communicate with the author of the article,or consult the relevant literature related to this compound(22426-30-8).
Reference:
Chapter 1 An introduction to palladium catalysis,
Palladium/carbon catalyst regeneration and mechanical application method