In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called Palladium-Catalyzed Siloxycyclopropanation of Alkenes Using Acylsilanes, published in 2022-01-26, which mentions a compound: 60748-47-2, mainly applied to mol structure optimized alkene acylsilane palladium complex; crystal structure mol siloxy cyclopropane preparation conversion ketone; palladium catalyst siloxycyclopropanation alkene acylsilane carbene electron rich, Product Details of 60748-47-2.
Currently, catalytically transferable carbenes are limited to electron-deficient and neutral derivatives, and electron-rich carbenes bearing an alkoxy group (i.e., Fischer-type carbenes) cannot be used in catalytic cyclopropanation because of the lack of appropriate carbene precursors. We report herein that acylsilanes can serve as a source of electron-rich carbenes under palladium catalysis, enabling cyclopropanation of a range of alkenes. This reactivity profile is in sharp contrast to that of metal-free siloxycarbenes, which are unreactive toward normal alkenes. The resulting siloxycyclopropanes serve as valuable homoenolate equivalent, allowing rapid access to elaborate β-functionalized ketones.
This compound(PD2DBA3)Product Details of 60748-47-2 was discussed at the molecular level, the effects of temperature and reaction time on the properties of the compound were discussed, and the optimum reaction conditions were selected.
Reference:
Chapter 1 An introduction to palladium catalysis,
Palladium/carbon catalyst regeneration and mechanical application method