A common heterocyclic compound, (2,2¡ä-Bipyridine)dichloropalladium(II), its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc., below Introduce a new synthetic route.”14871-92-2
First, 63.6 mg (0.2 mmol)Of compounds 111-5 and 32.2 mmol (0.6 mmol)Of methanol was added to a mixture of 30 ml of anhydrous methanol and tetrahydrofuran(Volume ratio of 1: 1)Argon protection,After stirring at room temperature for 1.5 h,Followed by the addition of 66.4 mg (0.2 mmol) of cis-dichloro-1,1′-bipyridyl palladium (II)Continue to argon protection,Stirring at 25 C for 14 h,After the reaction,The resulting solid was purified by column chromatography,Get the target product,Weight 93.8 mg, yield: 85%.
The chemical industry reduces the impact on the environment during synthesis,14871-92-2,(2,2¡ä-Bipyridine)dichloropalladium(II),I believe this compound will play a more active role in future production and life.
Reference£º
Patent; Changchun Institute of Applied Chemistry, Chinese Academy of Sciences; Wang, Zhiyuan; Liu, Bo; Qiao, Wenqiang; (34 pag.)CN103483391; (2016); B;,
Chapter 1 An introduction to palladium catalysis
Palladium/carbon catalyst regeneration and mechanical application method