Formula: C18H28ClRu. Aromatic heterocyclic compounds can also be classified according to the number of heteroatoms contained in the heterocycle: single heteroatom, two heteroatoms, three heteroatoms and four heteroatoms. Compound: Chloro(1,5-cyclooctadiene)(pentamethylcyclopentadienyl)ruthenium, is researched, Molecular C18H28ClRu, CAS is 92390-26-6, about Synthesis of 2-haloalkylpyridines via Cp*RuCl-catalyzed cycloaddition of 1,6-diynes with α-halonitriles. Unusual halide effect in catalytic cyclocotrimerization. Author is Yamamoto, Yoshihiko; Kinpara, Keisuke; Nishiyama, Hisao; Itoh, Kenji.
In the presence of 2-5 mol % Cp*RuCl(cod), various 1,6-diynes reacted with α-monohalo- and α,α-dihalonitriles at ambient temperature of afford 2-haloalkylpyridines in 42-93% isolated yields. The failure of acetonitrile, N,N-dimethylaminoacetonitrile, phenylthioacetonitrile, and Me cyanoacetate as nitrile substrate clearly showed that the α halogen substitution is essential for the present cycloaddition under mild conditions. The cycloaddition of unsym. diynes bearing a substituent on one alkyne terminal gave 2,3,4,6-substituted pyridines exclusively.
Different reactions of this compound(Chloro(1,5-cyclooctadiene)(pentamethylcyclopentadienyl)ruthenium)Formula: C18H28ClRu require different conditions, so the reaction conditions are very important.
Reference:
Chapter 1 An introduction to palladium catalysis,
Palladium/carbon catalyst regeneration and mechanical application method