Awesome Chemistry Experiments For 21797-13-7

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Room temperature C-H activation and cross-coupling of aryl ureas in water

(Chemical Equation Present) Just mix in water’n stir: Pd-catalyzed C-H activation/cross-couplings can be carried out at room temperature in water/surfactant mixtures. The combination of Pd-(OAc)2 and HBF 4 allowed for reactions of aryl ureas with aryl iodides under very mild conditions, using micellar catalysis (see scheme). This reaction is made possible by use of an in situ generated cationic palladium catalyst.

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Reference£º
Chapter 1 An introduction to palladium catalysis,
Palladium/carbon catalyst regeneration and mechanical application method