Awesome Chemistry Experiments For 7651-82-3

If you want to learn more about this compound(Isoquinolin-6-ol)Recommanded Product: 7651-82-3, you may wish to communicate with the author of the article,or consult the relevant literature related to this compound(7651-82-3).

In general, if the atoms that make up the ring contain heteroatoms, such rings become heterocycles, and organic compounds containing heterocycles are called heterocyclic compounds. An article called Photocatalytic redox-neutral hydroxyalkylation of N-heteroaromatics with aldehydes, published in 2020, which mentions a compound: 7651-82-3, Name is Isoquinolin-6-ol, Molecular C9H7NO, Recommanded Product: 7651-82-3.

Hydroxyalkylation of N-heteroaromatics with aldehydes was achieved using a binary hybrid catalyst system comprising an acridinium photoredox catalyst and a thiophosphoric acid organocatalyst. This metal-free hybrid catalysis proceeded under mild conditions for a wide range of substrates, including quinolines, isoquinolines and pyridines as N-heteroaromatics and both aromatic and aliphatic aldehydes to afford hydroxy-alkylated quinolines I [R = H, 6-F, 7-Br, etc; R1 = Me, Ph, propan-1-ol; R2 = Cl, propan-1-ol], hydroxy-alkylated isoquinolines II [R4 = Et, Ph, 4-FC6H4, etc.] and hydroxy-alkylated pyridines III [R5 = H, Br, Ph; R6 = C(O)Me, CO2Me]. The reaction was applicable to late-stage derivatization of drugs and their leads.

If you want to learn more about this compound(Isoquinolin-6-ol)Recommanded Product: 7651-82-3, you may wish to communicate with the author of the article,or consult the relevant literature related to this compound(7651-82-3).

Reference:
Chapter 1 An introduction to palladium catalysis,
Palladium/carbon catalyst regeneration and mechanical application method