In homogeneous catalysis, the catalyst is in the same phase as the reactant. The number of collisions between reactants and catalyst is at a maximum.In a patent, 95464-05-4, name is 1,1′-Bis(diphenylphosphino)ferrocene-palladium(II)dichloride dichloromethane complex, introducing its new discovery. SDS of cas: 95464-05-4
Biaryls were obtained in good to excellent yields from the palladium catalyzed reductive homocoupling reactions of various aryl iodides and bromides in dimethyl sulfoxide (DMSO) solution without the need for any additional reducing reagents. Pd(dppf)Cl2 is the most effective among the screened palladium catalysts for the homocoupling reactions. Fluorides, carbonates, acetates and hydroxides can be used as bases at promoting the palladium catalyzed reductive homocoupling of aryl halides in DMSO solution. X-ray photoelectron spectroscopic (XPS) analysis shows that the oxidative Pd2+(dppf) species can be reduced into the Pd0(dppf) active species by solvent DMSO molecules to furnish the catalytic cycle, indicating that DMSO plays a dual role as both solvent and reducing reagent. A plausible reaction mechanism has been discussed. Elimination of additional reducing reagents will not only reduce the reaction operation cost, but will also simplify the product separation and purification.
We’ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, the role of 95464-05-4, and how the biochemistry of the body works.SDS of cas: 95464-05-4
Reference：
Chapter 1 An introduction to palladium catalysis,
Palladium/carbon catalyst regeneration and mechanical application method