Reference of 5-Hydroxynicotinic acid. The fused heterocycle is formed by combining a benzene ring with a single heterocycle, or two or more single heterocycles. Compound: 5-Hydroxynicotinic acid, is researched, Molecular C6H5NO3, CAS is 27828-71-3, about Analysis of malondialdehyde and superoxide dismustase levels after exposure of electric cigarette in rats. Author is Lisdiana; Nugrahaningsih, W. H.; Nufus, I..
Elec. cigarette (e-cigarette) is cigarette that operate on battery power to burn liquids and to produce a steam. One of the contents of an elec. cigarette is nicotine. It is a chem. compound that can cause addiction and trigger oxidative stress. This study aims to analyze the levels of malondialdehyde and superoxide dismutase in the blood of rats that exposed to nicotine from e-cigarettes. The study was conducted on 30 male Wistar rats which divided into 5 groups, control group there are neg. and pos. and treatment group with nicotine 0,25 mg, 0,5 mg, 0,75mg with exposure to cigarette smoke for 30 days. Malondialdehyde and superoxide dismutase levels measurements using the TBARs method, the results that can be known using a spectrophotometer with a wavelength of 532 nm. SOD levels were measured by the calorimetry method. The One Way Anova anal. showed that malondialdehyde and superoxide dismutase levels in the control group were significantly different from all groups. The conclusion is that nicotine has an effect on increasing malondialdehyde and decreasing superoxide dismutase levels.
Different reactions of this compound(5-Hydroxynicotinic acid)Reference of 5-Hydroxynicotinic acid require different conditions, so the reaction conditions are very important.
Reference:
Chapter 1 An introduction to palladium catalysis,
Palladium/carbon catalyst regeneration and mechanical application method