Most of the natural products isolated at present are heterocyclic compounds, so heterocyclic compounds occupy an important position in the research of organic chemistry. A compound: 27828-71-3, is researched, SMILESS is O=C(O)C1=CN=CC(O)=C1, Molecular C6H5NO3Journal, Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya called Study of the kinetics of isotopic exchange of hydrogen in 5-hydroxynicotinic acid, Author is Lezina, V. P.; Stolyarova, L. G.; Shirokova, L. V.; Smirnov, L. D., the main research direction is hydroxynicotinic acid exchange kinetics; nicotinic acid hydroxy exchange kinetics; deuterium exchange hydroxynicotinic acid.Quality Control of 5-Hydroxynicotinic acid.
Kinetic studies of H-D exchange of 5-hydroxynicotinic acid (I) at 160° and pD 6.5-10.5 showed that only the 6-position of the ring underwent exchange. The rate constant for the step involving the dianion of I was determined
In addition to the literature in the link below, there is a lot of literature about this compound(5-Hydroxynicotinic acid)Quality Control of 5-Hydroxynicotinic acid, illustrating the importance and wide applicability of this compound(27828-71-3).
Reference:
Chapter 1 An introduction to palladium catalysis,
Palladium/carbon catalyst regeneration and mechanical application method