The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: 3-(2-Chlorophenyl)-5-isoxazolemethanol( cas:438565-33-4 ) is researched.Computed Properties of C10H8ClNO2.Shen, Chuansheng; Zhang, Yumin; Gan, Yuanming; Zhao, Tianqi; Gu, Qiang published the article 《One-pot synthesis of (3-phenylisoxazol-5-yl)methanol derivatives under ultrasound》 about this compound( cas:438565-33-4 ) in Letters in Organic Chemistry. Keywords: aldoxime propargyl alc dipolar cycloaddition ultrasound; phenylisoxazolyl methanol preparation ultrasonication. Let’s learn more about this compound (cas:438565-33-4).
An ultrasonic-assisted, one-pot, efficient, convenient procedure for the synthesis of (3-phenylisoxazol-5-yl)methanol derivatives was developed. (3-Phenylisoxazol-5-yl)methanol derivatives with biol. and pharmaceutical property were synthesized in moderate to excellent yields. The synthetic methods possess the advantages of high yield, facile operation process and shorter reaction time, and so on.
In addition to the literature in the link below, there is a lot of literature about this compound(3-(2-Chlorophenyl)-5-isoxazolemethanol)Computed Properties of C10H8ClNO2, illustrating the importance and wide applicability of this compound(438565-33-4).
Reference:
Chapter 1 An introduction to palladium catalysis,
Palladium/carbon catalyst regeneration and mechanical application method