Epoxy compounds usually have stronger nucleophilic ability, because the alkyl group on the oxygen atom makes the bond angle smaller, which makes the lone pair of electrons react more dissimilarly with the electron-deficient system. Compound: PD2DBA3, is researched, Molecular C51H42O3Pd2, CAS is 60748-47-2, about Pd-Catalyzed cross-coupling synthesis of 4-aryl-3-formylcoumarins.Name: PD2DBA3.
The threefold cross-coupling of triarylbismuth reagents BiAr3 (Ar = Ph, 4-methylphenyl, 3-fluorophenyl, etc.) with 4-chloro-3-formylcoumarins I (R = H, Cl; R1 = H, Me, OMe) furnished the corresponding 4-aryl-3-formylcoumarins II and III (R2 = C(O)OEt, 4-methoxyphenyl) in a chemoselective manner with high yields under Pd-catalyzed conditions. This method was successfully applied to electronically different triarylbismuth reagents and 4-chloro-3-formylcoumarins preserving the 3-formyl group in the coumarin scaffold.
Although many compounds look similar to this compound(60748-47-2)Name: PD2DBA3, numerous studies have shown that this compound(SMILES:O=C(/C=C/C1=CC=CC=C1)/C=C/C2=CC=CC=C2.O=C(/C=C/C3=CC=CC=C3)/C=C/C4=CC=CC=C4.O=C(/C=C/C5=CC=CC=C5)/C=C/C6=CC=CC=C6.[Pd].[Pd]), has unique advantages. If you want to know more about similar compounds, you can read my other articles.
Reference:
Chapter 1 An introduction to palladium catalysis,
Palladium/carbon catalyst regeneration and mechanical application method