The three-dimensional configuration of the ester heterocycle is basically the same as that of the carbocycle. Compound: Isoquinolin-6-ol(SMILESS: OC1=CC2=C(C=NC=C2)C=C1,cas:7651-82-3) is researched.Application In Synthesis of Aluminum triquinolin-8-olate. The article 《Synthesis of Indole-Dihydroisoquinoline Sulfonyl Ureas via Three-Component Reactions》 in relation to this compound, is published in Synthesis. Let’s take a look at the latest research on this compound (cas:7651-82-3).
Isoquinolines activated with sulfamoyl chlorides were reacted with indoles in a 3-component reaction to generate a library of dihydroisoquinoline derivs, e.g., I. Using a differential protecting group strategy, products were further derivatized. Synthesis of isoquinoline starting materials using several different methods was also described.
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Reference:
Chapter 1 An introduction to palladium catalysis,
Palladium/carbon catalyst regeneration and mechanical application method