Extracurricular laboratory:new discovery of Pd2(DBA)3

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Chemistry is traditionally divided into organic and inorganic chemistry. Computed Properties of C51H42O3Pd2, The former is the study of compounds containing at least one carbon-hydrogen bonds.In a patent,Which mentioned a new discovery about 52409-22-0

The invention belongs to the field, and belongs to the field of chemical synthesis. The invention specifically relates to a method for synthesizing chiral or non-chiral thioester compounds through palladium-catalyzed olefin carbonyl sulfide esterification. The synthesis process is conducted in a ventilation environment, and a palladium source, a ligand and a solvent are uniformly mixed, stirred 30 min, and the reaction solution; and an additive, an acid and an inhibitor, are added to the reaction solution to obtain a reaction solution; and the mixture, which is stirred at -20 C~25 C, reacts -20 C~25 C with the olefin, and is stirred at 12~24h. After completion of the reaction, the thioester compound. The invention provides a method, which can be used for post-modification of drugs, amino acids, polypeptides and the like under mild conditions through olefin insertion carbonyl sulfide esterification. (by machine translation)

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Reference:
Chapter 1 An introduction to palladium catalysis,
Palladium/carbon catalyst regeneration and mechanical application method