Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments. Recommanded Product: Tris(dibenzylideneacetone)dipalladium-chloroform. Introducing a new discovery about 52522-40-4, Name is Tris(dibenzylideneacetone)dipalladium-chloroform
A number of ethyl 2-aryl-2-formylpent-4-enoates containing acyclic, all-carbon, aryl-substituted quaternary stereocenters have been synthesized via intermolecular palladium-catalyzed asymmetric allylic alkylation (Pd-AAA). Here, a 2-aryl-3-hydroxyacrylate was used as an unprecedented nucleophilic counterpart instead of the widely used ketonic substrate. This produced a very rare, all-carbon chiral center including an easily utilized aldehyde or ketone moiety. Chiral ligand (R,R)-DACH-naphthyl Trost ligand was found to be optimal in this Pd-AAA reaction and provided good to excellent yields (75-99%) and enantioselectivities (52-94%) with a range of analogues. To show the utility of this method, it was used to synthesize an all-carbon quaternary, alpha,alpha-disubstituted beta-lactone.
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.Recommanded Product: Tris(dibenzylideneacetone)dipalladium-chloroform, you can also check out more blogs about52522-40-4
Reference：
Chapter 1 An introduction to palladium catalysis,
Palladium/carbon catalyst regeneration and mechanical application method