So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic.Zhang, Datong; Jia, Jiong; Meng, Lijuan; Xu, Weiren; Tang, Lida; Wang, Jianwu researched the compound: 3-(2-Chlorophenyl)-5-isoxazolemethanol( cas:438565-33-4 ).Recommanded Product: 3-(2-Chlorophenyl)-5-isoxazolemethanol.They published the article 《Synthesis and preliminary antibacterial evaluation of 2-butyl succinate-based hydroxamate derivatives containing isoxazole rings》 about this compound( cas:438565-33-4 ) in Archives of Pharmacal Research. Keywords: butyl succinate hydroxamate isoxazole derivative preparation SAR antibacterial activity. We’ll tell you more about this compound (cas:438565-33-4).
Two series of novel 2-Bu succinate-based Hydroxamate derivatives containing isoxazole rings, e.g. I [R = H, i-Bu], were synthesized, characterized and evaluated for antibacterial activity. The synthesized compounds were found to exhibit weak to moderate inhibitory activity against Staphytlococcusaureu and Klebsiellar pneumonia in vitro. All the compounds synthesized were found to be more effective against Klebsiellar pneumonia compared to Staphytlococcus aureu.
This compound(3-(2-Chlorophenyl)-5-isoxazolemethanol)Recommanded Product: 3-(2-Chlorophenyl)-5-isoxazolemethanol was discussed at the molecular level, the effects of temperature and reaction time on the properties of the compound were discussed, and the optimum reaction conditions were selected.
Reference:
Chapter 1 An introduction to palladium catalysis,
Palladium/carbon catalyst regeneration and mechanical application method