Computed Properties of C8H12N2O. Aromatic heterocyclic compounds can also be classified according to the number of heteroatoms contained in the heterocycle: single heteroatom, two heteroatoms, three heteroatoms and four heteroatoms. Compound: 5-Methyl-1-propyl-1H-pyrazole-4-carbaldehyde, is researched, Molecular C8H12N2O, CAS is 890652-02-5, about Identification of small-molecule inhibitors of Trypanosoma cruzi replication. Author is Germain, Andrew R.; Carmody, Leigh C.; Dockendorff, Chris; Galan-Rodriguez, Cristina; Rodriguez, Ana; Johnston, Stephen; Bittker, Joshua A.; MacPherson, Lawrence; Dandapani, Sivaraman; Palmer, Michelle; Schreiber, Stuart L.; Munoz, Benito.
We report the outcome of a high-throughput small-mol. screen to identify novel, nontoxic, inhibitors of Trypanosoma cruzi, as potential starting points for therapeutics to treat for both the acute and chronic stages of Chagas disease. Two compounds were identified that displayed nanomolar inhibition of T. cruzi and an absence of activity against host cells at the highest tested dose. These compounds have been registered with NIH Mol. Libraries Program (probes ML157 and ML158).
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Chapter 1 An introduction to palladium catalysis,
Palladium/carbon catalyst regeneration and mechanical application method