Most of the compounds have physiologically active properties, and their biological properties are often attributed to the heteroatoms contained in their molecules, and most of these heteroatoms also appear in cyclic structures. A Journal, Tetrahedron called Synthesis and characterization of an isopropylBippyPhos precatalyst, Author is Coffey, Steven B.; Bernhardson, David J.; Wright, Stephen W., which mentions a compound: 60748-47-2, SMILESS is O=C(/C=C/C1=CC=CC=C1)/C=C/C2=CC=CC=C2.O=C(/C=C/C3=CC=CC=C3)/C=C/C4=CC=CC=C4.O=C(/C=C/C5=CC=CC=C5)/C=C/C6=CC=CC=C6.[Pd].[Pd], Molecular C51H42O3Pd2, Category: catalyst-palladium.
A review of our high throughput reaction screening data revealed that BippyPhos was frequently associated with successful outcomes in Buchwald-Hartwig amination reactions. A barrier to the wider use of this ligand, particularly among those performing smaller scale work, may be the lack of a readily available precatalyst. We describe the multi-gram synthesis and characterization of isopropylBippyPhos, and its conversion to isopropylBippyPhos Pd G2, a biaryl phosphine precatalyst. We demonstrate the competency of isopropylBippyPhos Pd G2 in palladium catalyzed Buchwald-Hartwig amination reactions and in Suzuki-Miyaura cross-coupling reactions.
This literature about this compound(60748-47-2)Category: catalyst-palladiumhas given us a lot of inspiration, and I hope that the research on this compound(PD2DBA3) can be further advanced. Maybe we can get more compounds in a similar way.
Reference:
Chapter 1 An introduction to palladium catalysis,
Palladium/carbon catalyst regeneration and mechanical application method