Synthetic Route of C18H28ClRu. So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic. Compound: Chloro(1,5-cyclooctadiene)(pentamethylcyclopentadienyl)ruthenium, is researched, Molecular C18H28ClRu, CAS is 92390-26-6, about Synthesis of Spirocyclic C-Arylribosides via Cyclotrimerization.
Spirocyclic C-arylribosides, e.g. I, were synthesized from the known γ-ribonolactone derivative Lithium acetylide addition followed by stereoselective glycosylation with 3-(trimethylsilyl)propargyl alc. converted the ribonolactone to silylated diynes. After desilylation or iodination, subsequent ruthenium-catalyzed regioselective cycloaddition of resultant diynes with alkynes or chloroacetonitrile gave spirocyclic C-arylribosides. Palladium-catalyzed Mizoroki-Heck, Sonogashira and Suzuki-Miyaura coupling reactions of the spirocyclic C-arylribosides were also studied.
Different reactions of this compound(Chloro(1,5-cyclooctadiene)(pentamethylcyclopentadienyl)ruthenium)Synthetic Route of C18H28ClRu require different conditions, so the reaction conditions are very important.
Reference:
Chapter 1 An introduction to palladium catalysis,
Palladium/carbon catalyst regeneration and mechanical application method