Safety of PD2DBA3. The reaction of aromatic heterocyclic molecules with protons is called protonation. Aromatic heterocycles are more basic than benzene due to the participation of heteroatoms. Compound: PD2DBA3, is researched, Molecular C51H42O3Pd2, CAS is 60748-47-2, about Setup of 4-Prenylated Quinolines through Suzuki-Miyaura Coupling for the Synthesis of Aurachins A and B. Author is Stief, Laura; Speicher, Andreas.
A polyprenyl side chain could be introduced into the heterocyclic quinoline moiety through Suzuki-Miyaura coupling of the corresponding quinoline-N-oxide with a polyprenyl boronic acid. This tool could be utilized for the synthesis of the natural product Aurachin B from the myxobacterium Stigmatella aurantiaca. This prenylated quinoline could then be transformed into the related Aurachin A through an epoxidation-ring opening cascade.
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Reference:
Chapter 1 An introduction to palladium catalysis,
Palladium/carbon catalyst regeneration and mechanical application method