Epoxy compounds usually have stronger nucleophilic ability, because the alkyl group on the oxygen atom makes the bond angle smaller, which makes the lone pair of electrons react more dissimilarly with the electron-deficient system. Compound: 3-(2-Chlorophenyl)-5-isoxazolemethanol, is researched, Molecular C10H8ClNO2, CAS is 438565-33-4, about Efficient solvent-free synthesis of bis(indolyl)methanes on SiO2 solid support under microwave irradiation.COA of Formula: C10H8ClNO2.
An efficient synthesis of bis(indolyl)methanes I (R1 = C6H5, 3-pyridinyl, 4-CH3C6H4, etc.) was developed. Bis(indolyl)methanes were synthesized starting from various aromatic aldehydes with indole under microwave irradiation and solvent-free conditions (85-98%). Solid support SiO2 was found to possess favorable catalytic and dispersancy parameters for the condensation reaction. Moreover, novel bis(indolyl)methanes containing an isoxazole ring II (R2 = H, t-Bu, 4-Cl, etc.) were synthesized via this method in excellent yields (> 94%) using 3-substituted isoxazole-5-carbaldehydes and indole.
Here is a brief introduction to this compound(438565-33-4)COA of Formula: C10H8ClNO2, if you want to know about other compounds related to this compound(438565-33-4), you can read my other articles.
Reference:
Chapter 1 An introduction to palladium catalysis,
Palladium/carbon catalyst regeneration and mechanical application method