The effect of the change of synthetic route on the product 7651-82-3

Different reactions of this compound(Isoquinolin-6-ol)Product Details of 7651-82-3 require different conditions, so the reaction conditions are very important.

Most of the natural products isolated at present are heterocyclic compounds, so heterocyclic compounds occupy an important position in the research of organic chemistry. A compound: 7651-82-3, is researched, SMILESS is OC1=CC2=C(C=NC=C2)C=C1, Molecular C9H7NOJournal, Article, Journal of Organic Chemistry called Metal-Free Synthesis of Phenol-Aryl Selenides via Dehydrogenative C-Se Coupling of Aryl Selenoxides with Phenols, Author is Liu, Zhengfen; Jiang, Yonggang; Liu, Chunxiang; Zhang, Linlin; Wang, Jing; Li, Tiantian; Zhang, Hongbin; Li, Minyan; Yang, Xiaodong, the main research direction is phenol aryl selenide preparation; aryl benzyl selenoxide preparation phenol cross coupling.Product Details of 7651-82-3.

Herein, we disclose the synthesis of diaryl selenides through an unexpected C-Se coupling between aryl benzyl selenoxides and phenols. The synthetic significance of the method is that it provides a mild, rapid, and metal-free access to organoselenides in high yields with excellent functional group tolerance. This coupling of aryl benzyl selenoxides reveals a completely new reaction possibility compared with aryl sulfoxides. We also probed the reaction mechanism of this unexpected transformation through exptl. studies and revealed a special Se(IV)-Se(III)-Se(II) reaction pathway.

Different reactions of this compound(Isoquinolin-6-ol)Product Details of 7651-82-3 require different conditions, so the reaction conditions are very important.

Reference:
Chapter 1 An introduction to palladium catalysis,
Palladium/carbon catalyst regeneration and mechanical application method