The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: 2-Cyano-2-methylpropanoic acid( cas:22426-30-8 ) is researched.Product Details of 22426-30-8.Nagarajan, Srinivasan; Ganem, Bruce published the article 《Chemistry of naturally occurring polyamines. 10. Nonmetabolizable derivatives of spermine and spermidine》 about this compound( cas:22426-30-8 ) in Journal of Organic Chemistry. Keywords: spermine analog; spermidine analog. Let’s learn more about this compound (cas:22426-30-8).
The synthesis of five gem-dimethylspermidines, e.g., H2NCMe2CH2CH2NH(CH2)4NH2, and the 2 spermine analogs H2NCMe2CH2CH2NH(CH2)4NHCH2CH2CMe2NH2 and H2NCH2CH2CMe2NH(CH2)4NHCMe2CH2CH2NH2 was described. These compounds were designed to act as polyamine oxidase inhibitors and to serve as useful probes of complex polyamine biosynthesis.
After consulting a lot of data, we found that this compound(22426-30-8)Product Details of 22426-30-8 can be used in many types of reactions. And in most cases, this compound has more advantages.
Reference:
Chapter 1 An introduction to palladium catalysis,
Palladium/carbon catalyst regeneration and mechanical application method