Epoxy compounds usually have stronger nucleophilic ability, because the alkyl group on the oxygen atom makes the bond angle smaller, which makes the lone pair of electrons react more dissimilarly with the electron-deficient system. Compound: Chloro(1,5-cyclooctadiene)(pentamethylcyclopentadienyl)ruthenium, is researched, Molecular C18H28ClRu, CAS is 92390-26-6, about Cp*RuCl(COD) in catalysis: A unique role in the addition of diazoalkane carbene to alkynes.Name: Chloro(1,5-cyclooctadiene)(pentamethylcyclopentadienyl)ruthenium.
A review. The catalytic transformations of functional alkynes with diazoalkanes in the presence of the catalyst precursor RuCl(COD)Cp* are presented. They show the unique role played by the Ru(X)Cp* moiety in catalysis and that the nature of the formed products strongly depends on the alkyne functionality. Simple alkynes generate dienes via double diazoalkane carbene addition to the triple bond. Enynes with terminal triple bond lead to alkenyl bicyclo[x.1.0]alkanes, including bicyclic aminoacid derivatives 1,6-enynes with disubstituted propargylic C produce in priority alkenyl alkylidene cyclopentanes. 1,6-Allenynes offer the direct access to alkenyl alkylidene bicyclo[3.1.0]hexanes. Propargylic carboxylates lead to conjugated dienes by coupling of the diazoalkane carbene with the alkyne terminal C and 1,2-shift of the carboxylate. All catalytic reactions can be explained by the initial formation of the 16 electron RuCl(=CHR)Cp* moiety giving 1st a 2+2 cycloaddition with the alkyne triple bond.
《Cp*RuCl(COD) in catalysis: A unique role in the addition of diazoalkane carbene to alkynes》 provides a strategy for the preparation of materials with excellent comprehensive properties, which is conducive to broaden the application field of this compound(Chloro(1,5-cyclooctadiene)(pentamethylcyclopentadienyl)ruthenium)Name: Chloro(1,5-cyclooctadiene)(pentamethylcyclopentadienyl)ruthenium.
Reference:
Chapter 1 An introduction to palladium catalysis,
Palladium/carbon catalyst regeneration and mechanical application method